Wales, the Midlands and Merseyside are set for severe snow and freezing temperatures tomorrow, with blizzard warnings for some regions.
Amber "be prepared" and yellow "be aware" warnings have been issued across the country, with officials advising residents, businesses and drivers to prepare for the worst.
Wales could face “severe disruption” tomorrow and forecasters warning of blizzard conditions in parts of the country.
More than three to six inches of snow is forecast to fall on Merseyside throughout tomorrow, with five inches due to fall on Liverpool.
Meanwhile, the Midlands could be hit with more than a foot of snow, with the region due to suffer up to 14 hours of blizzards.
Greater Manchester will be particularly hard hit, with up to eight inches of snow predicted for the city.
Elsewhere in the country, temperatures could plunge even lower with some forecasts of -15C temperatures.
With plummeting temperatures the weather is likely to cause chaos across cities for commuters and motorists, as the snow is expected to disrupt both morning and evening rush hours.
London and the South East is braced for wintry weather, with snow expected to arrive at 9am but ease off in the afternoon.
A Met Office spokesman said: “Clearly there is the potential for some severe disruption, and the public are advised to watch for updates to this warning and to be prepared to alter travel plans.”
Met Office forecaster Dan Williams said the weather could affect fans travelling to weekend Manchester sports fixtures.
Manchester City have a 3pm kick-off on Saturday afternoon at the Etihad stadium against Fulham while United play away in London, against Tottenham, on Saunday.
Mr Williams said: “Thursday is expected to be pretty decent, dry through the day with bright spells. But in the early hours of Friday, there is a weather front pushing in from the west which is interacting with a cold air stream over the UK."
Steve Crosthwaite, head of the Highways Agency’s National Traffic Operations Centre, said: “We advise drivers to check road conditions and the Met Office weather forecast before they set off and during severe weather to consider whether their journey is essential.
Posted on the Mirror Online, January 2013.